| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6e960aa6ad2ba6401030159343ebe68 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C313-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C319-20 |
| filingDate |
1988-02-17^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1989-12-12^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29cc80fed5dcacdb99b8fb94ae1cce0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_686c00fa0664990963c33689b0227ee3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2920e2266b1477c362105a47c63d2076
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c3ef64fda50cf25e9e10ab732da9dbf |
| publicationDate |
1989-12-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4886910-A |
| titleOfInvention |
Cyanoguanidine derivative and process for preparation thereof |
| abstract |
The present invention provides a cyanoguanidine derivtive which is a precursor for the synthesis of N-cyano-N'-methyl-N"-[2-{(5-methyl-1H-imidazol-4-yl)methylothio}ethyl]-guanidine (Cimetidine) or its relted compound, which has an action of controlling secretion of acid in the stomach based on the histamine H 2 receptor antagonism and is valuable as a drug for treating gastric ulcer. This cyanoguanidine derivative is prepared by reacting a haloketone derivative with an ammonium salt and a lower fatty acid salt or by reacting other cyanoguanidine derivative with an ammonium salt. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6552045-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6353005-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6548518-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022034121-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6362202-B1 |
| priorityDate |
1987-02-17^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |