| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f9af914ed2fb00cd4f1b8b1a28964e4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-64 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-54 |
| filingDate |
1989-04-25^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1990-04-10^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad9f70fb8facf317c060bf017dd6aa96
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d187e529e29e9b9bf59947cdd73101e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9909d5d2b5fb3b9223810e0278cadeb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af84559256592231d3274832e2972556 |
| publicationDate |
1990-04-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4916233-A |
| titleOfInvention |
Method for production of 4-methyl-5-(2-aminoethyl)-thiomethyl)-imidazole |
| abstract |
4-Methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole can be effectively produced by causing 4-methylimidazole or a salt thereof to react with at least one member selected from the group consisting of (a) a formaldehyde adduct of cysteamine, (b) 2-aminoethanethiol sulfuric acid and formaldehyde or a formaldehyde oligomer, and (c) thiazolidine or a salt thereof, in the presence of a mineral acid, removing a portion of reaction liquid out of the reaction system while maintaining molar concentration of 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole in the reaction system not exceeding 70 mol % based on total mol numbers of 4-methylimidazole and 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole, then separating a liquid containing 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole from the removed portion of reaction liquid, and recycling the remainder into the reaction system. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9006480-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5756822-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102844297-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102844297-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009123751-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5064964-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011130032-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5408524-A |
| priorityDate |
1988-04-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |