http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5037633-A

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filingDate 1990-08-16^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-08-06^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1991-08-06^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5037633-A
titleOfInvention Microbiologically stabilized phase for bicarbonate toothpaste manufacture
abstract The invention provides a process for microbiologically stabilizing a premix phase intended to receive bicarbonate in the manufacture of toothpaste. The process includes blending together in the premix phase a polyol, a thickening agent, a copper compound and water. The premix phase is maintained at a temperature no higher than 110° F. for a time sufficient to destroy bacteria. Thereafter the bicarbonate is incorporated into the premix phase without cool-down of the premix phase. There is also disclosed an oral composition that includes a combination of humectant, thickening agent, copper, bicarbonate and water.
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