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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-24
filingDate 1989-02-08^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-09-17^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1991-09-17^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5049494-A
titleOfInvention Conversion of mannose to fructose
abstract An economical method of converting mannose to fructose uses a mannose isomerase from Pseudomonas cepacia immobilized on an alumina containing polyethyleneimine crosslinked with an excess of glutaraldehyde. The method utilizes mannose-containing aqueous solutions as the feedstock, and affords solutions in which at least 55% of the mannose has been converted to fructose. Because of the relatively higher levels of fructose than can be obtained by isomerizing glucose to fructose using glucose isomerase, substantial savings in separation of high fructose-containing products can be achieved. The process described represents the first economical mannose isomerase process.
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