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filingDate 1988-08-19^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1991-11-26^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5b325329a81a29fc93d58d42237c2b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2431f081977054ac0233cabaf9c08d6f
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publicationDate 1991-11-26^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5068314-A
titleOfInvention Lipopolysaccharide-binding polypeptide
abstract PCT No. PCT/JP88/00823 Sec. 371 Date Aug. 19, 1989 Sec. 102(e) Date Aug. 19, 1989 PCT Filed Aug. 19, 1988 PCT Pub. No. WO89/01492 PCT Pub. Date Feb. 23, 1989.This invention relates to a novel polypeptide represented by the formula: <IMAGE> (1) (wherein Lys represents lysine, Trp tryptophan, Cys cystine, Phe phenylalanine, Arg arginine, Val valine, Tyr tyrosine, Gly glycine, Ile isoleucine and X a hydroxyl group or an amino group), its analogue and a method for preparing the same. The polypeptide exhibits strong affinity for lipolysaccharide, and is useful for removing endotoxin and as a therapeutic agent of bacterial infections.
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