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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-209
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24
filingDate 1989-04-12^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1992-02-04^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afb014fe87faa6e67bef920b8f7e2c0a
publicationDate 1992-02-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5085865-A
titleOfInvention Sustained release pharmaceutical preparations containing an analgesic and a decongestant
abstract An orally administrable sustained-release pharmaceutical tablet having at least two layers, which are directly compressible, is disclosed. The first layer, an immediate-release layer, contains an orally active analgesic and is readily susceptible to disintegration in the stomach. The second layer, a sustained-release layer which is directly compressed onto the first layer, comprises an orally active decongestant admixed with a major amount of a sustained-release agent so as to display increased resistance to disintegration and erosion in the gastro-intestinal tract relative to the first layer.
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