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filingDate 1987-08-24^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc450f4f5c52b6e2dc223d890b495b21
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publicationDate 1992-08-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5136033-A
titleOfInvention Ion selective fluorogenic reagents
abstract Novel fluorogenic ionophores have been synthesized which selectively bind ions such as potassium and sodium, even in neutral aqueous and alcoholic media and respond to such binding by fluorescence quenching or enhancement. These ionophores are ideal for the selective and direct determination of ions in biological or environmental samples and the like. The ionophores are also suitable for incorporation into fiber optic-based sensors for the continuous in vivo or in vitro monitoring of metal ions in blood or other biological fluids.
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