abstract |
There are described compounds of the formula <IMAGE> where A is CH or N; X is hydrogen, loweralkyl, halogen, trifluromethyl, loweralkoxy, arylloweralkoxy, hydroxy or phenylamino; Y is hydrogen, loweralkyl, halogen, loweralkoxy, arylloweralkoxy or hydroxy; R1 is hydrogen or loweralkyl; R2 is hydrogen, loweralkyl, formyl, alkylcarbonyl, arylloweralkylcarbonyl, arylcarbonyl, alkoxycarbonyl, arylloweralkoxycarbonyl or aryloxycarbonyl; R3 is hydrogen, alkyl, alkylcarbonyl, arylloweralkylcarbonyl, arylcarbonyl, alkoxycarbonyl, arylloweralkoxycarbonyl, aryloxycarbonyl or -CH2CO2C2H5; which compounds are useful as topical antiinflammatory agents for the treatment of skin disorders. |