| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79751aeaa9923745648e5ae7d9c35782 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-572 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-58 |
| filingDate |
1991-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1993-06-08^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08c81f2228ab5c2b37037e532af6edcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67cc8af86540d70ef44698c66039381a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be5108f81f62a9062059ccbf1ffe944a |
| publicationDate |
1993-06-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5217963-A |
| titleOfInvention |
Certain phosphonic acid quinoline-2-carboxylic acids, esters or amides useful for treatment of disorders responsive to N-methyl D-aspartate receptor blockade |
| abstract |
The present invention is concerned with the phosphonic acids of formula I <IMAGE> (I) wherein one or both of the acidic hydroxy groups of the phosphonic acid moiety may be functionalized in form of pharmaceutically acceptable mono- or di- esters; wherein Y represents optionally substituted 2-carboxytetrahydroquinolinyl or 2-carboxyperhydroquinolinyl, and in each of which the carboxy group may be functionalized in form of a pharmaceutically acceptable ester or amide; A represents a direct bond, lower alkenylene, lower alkylidene or lower alkylene; and pharmaceutically acceptable salts thereof; which are useful for the treatment of nervous system disorders in mammals and as antagonists of the N-methyl-D-aspartate sensitive excitatory amino acid receptor. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106831540-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5342946-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5710139-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9517410-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5538958-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5326756-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006148776-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5510338-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-686722-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006067953-A1 |
| priorityDate |
1985-05-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |