| abstract |
A medical member having active hydrogen groups such as hydroxyl, amino or imino groups at its surface, is dipped, either directly or after formation of an inner layer on its surface, into a solution. The solution is prepared by dissolving a surface active material, e.g., CF b 3 (CF 2 ) 7 (CH 2 ) 2 SiCl 3 in a non-aqueous solvent. A dehydrochlorination reaction is brought about between active hydrogen groups at the surface of the member and SiCl groups of the surface active material, thus producing bonds of n n CF.sub.3 (CF.sub.2).sub.7 (CH.sub.2).sub.2 Si(O--).sub.3 n n over the entire surface. A fluorine-containing monomolecular film is formed, which is chemically (or covalently) bonded to the member surface and has a thickness at the nanometer level. Since the chemically adsorbed film is covalently bonded to the member or inner layer, it is chemically stable and difficult to separate. Excellent medical members can be obtained when the invention is applied to an artificial tooth, a joint, a bone, a blood bag, a catheter, a blood transportation tool, a dialysis equipment part, an operation thread, a medical implant and an operation tool. |