| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8e5f9558d21d0622d522d515f99fcd1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-55 |
| filingDate |
1995-06-05^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-03-19^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4860868b8dc75dfb2da6083b93ef5460
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6104c53c0f16105dd2b44a28f03e04e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_351ae60c10a7df317261871035edf74c |
| publicationDate |
1996-03-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5500370-A |
| titleOfInvention |
Thermostable ribonuclease H and genetic constructs therefore |
| abstract |
An essentially pure preparation of thermostable RNase H isolated from Thermus flavus is disclosed. In one preferable form of the invention, the RNase H is capable of biological activity after incubation at temperatures equal to or greater than 70 DEG C. for at least ten minutes. The present invention is also a method of digesting RNA polymers that are in duplex form with a DNA molecule. The method comprises exposing the duplex to the isolated thermostable RNase H. The present invention is also a genetic construct capable of expressing a thermostable RNase H. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009142754-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014152659-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007254327-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003104378-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006194209-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004197802-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7935800-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6780632-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022256597-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6759226-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003186238-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008138879-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011104682-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-755520-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8063184-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7045289-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7306929-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004048596-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7150982-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2410049-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008293046-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9953018-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9953018-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7807806-B2 |
| priorityDate |
1991-12-27^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |