| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76195fd1cd08192222699d8e7a88c231 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F7-1892
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-29 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-347
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C35-04 |
| filingDate |
1994-11-04^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d024111dbda291f6cf93231c8a1a911
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0263c60a9df2106874df5f2f21841bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_506fac026de18a98b89d9d2a82f4f9d5 |
| publicationDate |
1996-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5516903-A |
| titleOfInvention |
Process for preparing [IR-(1α,2β-3α)]-2-amino-9-[2,3-bis(hydroxymethyl)cyclobutyl]-1,9-dihydro-6H-purin-6-one |
| abstract |
The protected cyclobutanone of the formula ##STR1## is treated with a dialkylaluminum chloride, an alkylaluminum dichloride, a trialkylaluminum compound, hydrogen in the presence of the catalysts ruthenium black or ruthenium on alumina, diphenyl-silane in the presence of tris(triphenylphosphine) rhodium (I) chloride, or iridium tetrachloride to yield the corresponding diprotected cyclobutanol. This compound is useful as an intermediate in the preparation of antiviral agents. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015059703-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11286053-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421552-B2 |
| priorityDate |
1992-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |