abstract |
PCT No. PCT/CH91/00235 Sec. 371 Date Feb. 10, 1993 Sec. 102(e) Date Feb. 10, 1993 PCT Filed Nov. 15, 1991 PCT Pub. No. WO92/08709 PCT Pub. Date Mar. 29, 1992.D,L-, L- and D-phenyl alanine derivatives of formula (I) defined in claim 1 in which R1 is an amidino-, guanidino-, oxamidino-, aminomethyl- or amino group have been discovered which effectively prevent blood coagulation or thrombosis. The antithrombotically active compounds have low toxicity and may be administered by mouth, subcutaneously or intravenously. |