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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
filingDate 1995-05-31^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-11-26^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34de04b236f2f5e912bbab58b8c7a10c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_206668c4f1d9cff1b973cfab06fbb440
publicationDate 1996-11-26^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5578450-A
titleOfInvention Tumor-specific genomic instability as a prognostic indicator
abstract A method for assessing the level of genomic instability in a malignant tumor is described. The method involves comparison of the structure of one or more interspersed repetitive sequence loci in tumor and corresponding normal tissue samples. Microsatellite repetitive sequences are one useful form of interspersed repetitive sequence that may be employed to characterize the genomic instability associated with some malignant tumors. This assessment provides an additional prognostic indicator for patients having such malignant tumors.
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