http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5597909-A

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filingDate 1994-08-25^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1997-01-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1997-01-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5597909-A
titleOfInvention Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
abstract Methods and reagents are provided for synthesizing polynucleotides containing modified deoxyribose residues. Monomeric reagents having the structural formula (I) ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are as defined herein, are used to create polynucleotides having nonnucleotidic moieties -A-Z-(R 9 ) n at the 1 position of selected deoxyribose units. The polynucleotides so provided are useful in a variety of hybridization assay formats.
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