| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f608437b78674d77bd371f635a364d56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63dfc8b1bce837a93a49230c74be18f4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S530-826
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-80
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-20022 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12 |
| filingDate |
1995-05-31^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-04-01^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27c5803fc71c8d6a2178556336e312c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51625d9f2a07412769cc1c80cd30c550 |
| publicationDate |
1997-04-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5616559-A |
| titleOfInvention |
Papillomavirus E2 trans-activation repressors |
| abstract |
This invention relates to E2 trans-activation repressors which interfere with normal functioning of the native full-length E2 transcriptional activation protein of the papillomavirus. Native full-length E2 trans-activation protein activates transcription of papillomavirus only through binding to DNA, and it binds to DNA only in the form of a pre-formed homodimer-a pair of identical polypeptide subunits held together by non-covalent interactions. The E2 trans-activation repressors of this invention are proteins, polypeptides or other molecules that dimerize with full-length native E2 polypeptides to form inactive heterodimers, thus interfering with the formation of active homodimers comprising full-length native E2 polypeptides, thereby repressing papillomavirus transcription and replication. The E2 trans-activation repressors of this invention are advantageously used in the treatment of papillomavirus infections and their associated diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9663556-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7485708-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005208482-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003202980-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6645501-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005226890-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011195078-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008155703-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004234548-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005063994-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010166802-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004146889-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003049237-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7927580-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10159707-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7879977-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8153414-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005244434-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8815251-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6495526-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004208894-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8246945-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9206239-B2 |
| priorityDate |
1991-01-28^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |