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publicationDate 1997-04-29^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5624839-A
titleOfInvention Process for culturing hepatocytes for formation of spheroids
abstract Hepatocytes spheroids can be formed by culturing hepatocytes in a culture vessel using a lipid-bound glycosaminoglycan as a culture substrate. Floating spheroids of hepatocytes can be obtained efficiently, which are capable of maintaining liver-specific functions and of keeping the spheroid form stably for a prolonged period of time.
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