| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33c922e05f6133b7d72dbb849d77487d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06139 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-078 |
| filingDate |
1996-06-06^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1997-10-21^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d34484fa02eab8659360e74c3eff2392
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3934f13017e034135a2bcc4a5a3b50b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15ae6c32b758521f48b17e7eb41c19b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90d919d36444d5d30afd5ad843902e33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571066725b97b6adbf600e41c3b5d0fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cd4f747ede3078be9c0c52da3f4a098
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d6c6e3cdd6efcde814a2b46125cdb980
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_82718bb4679c7574d9705e4c703a0cb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bc047f33f63c9b0bd323e175504774b |
| publicationDate |
1997-10-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5679687-A |
| titleOfInvention |
Irreversible HIV protease inhibitors, compositions containing same and process for the preparation thereof |
| abstract |
The present invention relates to novel compounds of formula (I) which have inhibitory activity against human immunodeficiency virus ("HIV") protease, a process for the preparation thereof, and compositions for prevention or treatment of AIDS by HIV infection comprising the above compounds as active ingredients. <IMAGE> (I) wherein: R1 is an aromatic group, a nitrogen-containing aromatic group, C1-4 alkyl group optionally substituted with an aromatic group or a nitrogen-containing aromatic group, C1-4 alkoxy group optionally substituted with an aromatic group or a nitrogen-containing aromatic group; R2 is an amino acid residue or a C1-8 alkyl group substituted with a C1-4 alkylsulfonyl group; R3 is a C1-4 alkyl group optionally substituted with an aromatic group; R4 is hydrogen or a C1-4 alkyl group; R5 is an aromatic group, a C1-10 alkyl group or a C1-4 alkyl groups optionally substituted with an aromatic group; and n is 1 or 2. |
| priorityDate |
1993-11-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |