abstract |
A guanidine derivative represented by formula (1), (2), (3) or its acid addition salt and a production process thereof <IMAGE> (1) <IMAGE> (2) alkylene, D is a single bond, -CO- or a C1-C5 alkylene, E is H, a lower alkyl or the like, m is 1 to 6, n is 0 to 6 and R1 is H, a lower alkyl or the like, l is 1 to 10 and G is H, -OH or the like and a skin cosmetic containing the same. It can exert excellent keratin layer softening effect continuously for a long period of time. |