abstract |
PCT No. PCT/EP93/03611 Sec. 371 Date Nov. 15, 1996 Sec. 102(e) Date Nov. 15, 1996 PCT Filed Dec. 20, 1993 PCT Pub. No. WO94/14798 PCT Pub. Date Jul. 7, 1994The instant invention is a compound of formulaA-X-Y-En-R5in which A is a bis-indolylmaleinimide or indolopyrrolocarbazole useful in the treatment and/or prevention of cancer, viral diseases, thrombosis, heart rhythm disturbances, atherosclerosis, bronchopulmonary diseases, degenerative diseases of the central nervous system, inflammatory diseases, diseases of the immune system, psoriasis, and immune suppression. A pharmaceutical composition and methods of preparing the compounds are also included. |