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filingDate 1995-06-06^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1998-05-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5750767-A
titleOfInvention Synthesis and use of amino acid fluorides as peptide coupling reagents
abstract The present invention is directed to the process of preparing a peptide comprising reacting a first amino acid or peptide with an amino acid fluoride of the formula: <IMAGE> or the acid fluoride salts thereof wherein BLK is an N-amino protecting group AA is an amino acid residue and X is H or a protecting group useful, and the first amino and peptide have a free amino group and a blocked carboxy end.
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