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titleOfInvention Compounds derived from boronic acid
abstract Compound of formula (I) ##STR1## in which: R 1 and R 2 , which are identical or different, represent hydrogen or alkyl or alternatively R 1 and R 2 form, with the carbon atom which bears them, cycloalkyl, n R 3 represents hydrogen or alkyl, phenyl or benzyl, n R 4 represents: n optionally substituted amino, optionally substituted amindino, optionally substituted guanidino, optionally substituted isothioureido, optionally substituted iminomethylamino, mercapto substituted with heterocyclic, or heterocyclic, n R 5 and R 6 each represent hydrogen or alkyl, or ##STR2## forms a boronic ester of pinanediol, m represents an integer such that 0≦m≦6, n n represents an integer such that 1≦n≦6, n A represents any one of the following groups: n * optionally substituted bicycloalkyl (C 5 -C 10 )phenyl, n * or a group of formula: ##STR3## A 1 represents --CO--, --CS--, --SO 2 --, the isomers thereof and the addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same are useful as trypsin-like serine proteases.
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