| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S930-143 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-241
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-5255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-242 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-19 |
| filingDate |
1995-05-19^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1998-10-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6f98137a328cdb25ecc3dbf959c41fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd65508e78176160d5cf058c9b893cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_73cfc11d5218d25ae3654e9bbdde1e4a |
| publicationDate |
1998-10-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5824509-A |
| titleOfInvention |
Recombinant lymphotoxin cDNA and variants |
| abstract |
Biologically active lymphotoxin polypeptides are synthesized in recombinant cell culture. Novel nucleic acid and vectors incorporating same are provided. The compositions and processes herein enable the economical preparation of compositions containing uniform lymphotoxin polypeptides and variant lymphotoxins having amino acid sequences that differ from those found in nature. The lymphotoxins are purified to a specific activity of 2-10x107 units/mg of protein by purification using a novel immobilized, lymphotoxin-neutralizing monoclonal antibody. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004265344-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011150865-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9616114-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011060015-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011208673-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11129906-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8642740-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003162217-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11180535-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11633435-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828356-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3360567-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729731-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8216807-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10449237-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7923011-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8541552-B2 |
| priorityDate |
1984-05-31^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |