http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5922759-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05ff905fdc49089f5f25746eaeb40190 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D407-04 |
| filingDate | 1996-06-21^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1999-07-13^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_103625bbf364d60904c28b75b451298e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b156211f57bb9f18f27f829696efb03b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_977494135a5c2616409f9bcb50ca535a |
| publicationDate | 1999-07-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-5922759-A |
| titleOfInvention | Butenolide endothelin antagonists |
| abstract | PCT No. PCT/US96/10651 Sec. 371 Date Dec. 15, 1997 Sec. 102(e) Date Dec. 15, 1997 PCT Filed Jun. 21, 1996 PCT Pub. No. WO97/02265 PCT Pub. Date Jan. 23, 1997Novel nonpeptides characterized as having a carbarimic group which are antagonists of endothelin I are described, as well as methods for their preparation and pharmaceutical compositions containing the same. The compounds as useful in treating elevated levels of endothelin and are therefore used in the treatment of hypertension, myocardial infarction, diabetes, cerebral vasospasm, cirrhosis, septic shock, congestive heart failure, endotoxic shock, subarachnoid hemorrhage, arrhythmias, asthma, chronic and acute renal failure, preeclamnpsia, atherosclerotic disorders including Raynaud's disease and restenosis, angina, cancer, pulmonary hypertension, ischemic disease, gastric mucosal damage, hemorrhagic shock, stroke, head injury, and ischemic bowel syndrome. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010022568-A1 |
| priorityDate | 1996-06-21^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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