| abstract |
PCT No. PCT/AU96/00151 Sec. 371 Date Jan. 23, 1998 Sec. 102(e) Date Jan. 23, 1998 PCT Filed Mar. 21, 1996 PCT Pub. No. WO96/30341 PCT Pub. Date Oct. 3, 1996The invention provides novel sulphonylurea, sulphonylthiourea and sulphonylguanidine compounds which have the ability to block potassium ion channels regulated by intracellular concentrations of ATP. Methods of synthesis, pharmaceutical compositions and methods for the treatment of conditions such as type II diabetes, cardiac arrhythmias, ischaemic and hypoxic cardiovascular incidents, and cancers are also claimed. |