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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
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filingDate 1997-01-07^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2000-09-05^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afc7bdfcd709c42422cb6b88b05849d6
publicationDate 2000-09-05^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6113876-A
titleOfInvention Methods of increasing sphincter competence
abstract A method of increasing sphincter competence comprising administering to a human in need of treatment an effective amount of a compound having the formula wherein R1 and R3 are independently hydrogen, wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidino, hexamethyleneimino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof. Also encompassed by the invention is a method of inhibiting urinary or fecal incontinence, or gastroesophageal disease or its symptoms, which includes administering to a human in need thereof an effective amount of a compound of formula 1.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003235529-A1
priorityDate 1996-01-29^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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