http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6140510-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c902faf6ae746c51fc8010672fc22894 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-09 |
| filingDate | 1999-05-10^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2000-10-31^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7ce253e370cba82dc9acc80292beb5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fedaf97120db8c14c9dbff471b04a9b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1540dd77e2babc7ba808a94d4ebe523 |
| publicationDate | 2000-10-31^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-6140510-A |
| titleOfInvention | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines |
| abstract | This invention relates to processes for the synthesis of various optically active amino pyrrolidinyl stereoisomers, or enantiomers, that may be attached to quinolonecarboxylic acids or naphthyridones. Processes and essential intermediates are disclosed and claimed for the synthesis of compounds represented by the structure shown in figure BG 4-1 , below. ##STR1## where R 50 , R 6 and R 9 are defined independently and are H, --(C 1 -C 8 )alkyl, --(C 3 -C 8 )cycloalkyl, --(C 1 -C 8 )alkyl-(C 3 -C 8 )cycloalkyl, --(C 6 -C 12 aryl), --(C 1 -C 8 )alkyl-(C 6 -C 12 aryl), or the aryl or alkyl is substituted with one to three of the following groups, (C 6 -C 12 aryl), (C 1 -C 3 )alkyl, (C 1 -C 3 ) alkoxy, halogen, trifluoromethyl; n where R 2 is --(C 1 -C 8 )alkyl, --(C 3 -C 8 )cycloalkyl, --(C 1 -C 8 )alkyl-(C 3 -C 8 )cycloalkyl, --(C 6 -C 12 aryl), --(C 1 -C 8 )alkyl-(C 6 -C 12 aryl), or the aryl or alkyl is substituted with one to three of the following groups, --(C 6 -C 12 aryl), --(C 1 -C 3 )alkyl, --(C 1 -C 3 ) alkoxy, halogen, trifluoromethyl; n depending upon the starting materials used, compounds represented by the structure shown by figure BG 4-1 may have one of either of the two steriochemical arrangments shown, or, if the starting materials are a racemic mixture, the reaction may produce a 1:1 ratio of the combination of products shown in Figure BG 4-1 , i.e. a racemic mixture. |
| priorityDate | 1993-05-06^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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