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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-355
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-355
filingDate 2001-02-27^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-02-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_160e6895b00d4989d042a0a4e2e00ee7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13eafc1848eb8d4d9d089d76d77672d1
publicationDate 2002-02-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6346544-B2
titleOfInvention Desmethyl tocopherols for protecting cardiovascular tissue
abstract The present invention involves the use of desmethyl tocopherols such as gamma tocopherol for the protection of cardiovascular tissue from nitrative stress. While mechanisms other than scavenging of reactive nitrogen species may be involved, desmethyl tocopherols exhibit significant protection and may be utilized to treat or help prevent cardiovascular particularly arterial vascular disease. The desmethyl tocopherols may be administered dietarily or parenterally when a more direct dosage is desired. Both routes may be utilized together or separately to optimize therapeutic and prophylactic benefits. The lessening of damage induced by reactive nitrogen species leads to the lessening of arterial blockage in thrombosis.
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