http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6358719-B1

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filingDate 2000-05-10^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-03-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06bdd3d915ea0b543ccbbbfa89d428a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1629b37297e291411ed84c9be376d34a
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publicationDate 2002-03-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6358719-B1
titleOfInvention Genes for the biosynthesis of epothilones
abstract Nucleic acid molecules are isolated from Sorangium cellulosum that encode polypeptides necessary for the biosynthesis of epothilone. Disclosed are methods for the production of epothilone in recombinant hosts transformed with the genes of the invention. In this manner, epothilone can be produced in quantities large enough to enable their purification and use in pharmaceutical formulations such as those for the treatment of cancer.
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