| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5c2d6a5a07914730d77e365aec0bf14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D217-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-557 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D217-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-24 |
| filingDate |
2000-08-18^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2002-04-02^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_720324211ff163bde6aa46ab33aab80e |
| publicationDate |
2002-04-02^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6365590-B1 |
| titleOfInvention |
Compounds, compositions and methods for treating erectile dysfunction |
| abstract |
Vasoactive compounds are described for the treatment of erectile dysfunction and impotence. The compounds are reaction products of an anionic or negatively charged vasoactive or erection-inducing component (such as alprostadil) and a cationic or positively charged vasoactive or erection-inducing component (such as prazosin) or a local anesthetic (such as lidocaine). These components are combined as acids and bases to form an organic salt or ionically bonded compound. The compounds have advantageous solubility characteristics and efficacy. A compound of the invention is combined with a pharmaceutical vehicle to form a composition which preferably includes an emulsifier. A local anesthetic and/or androgenic steroids may also be included. Compositions of the invention may also include more than one vasoactive organic salt compound. The composition can be advantageously formulated and administered to allow self-adjusted dosing, while minimizing or preventing overdosing. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004185097-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8986188-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004076671-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8841345-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004241245-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009082617-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009054497-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009054498-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1605928-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103319390-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103319390-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9113989-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9056044-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017168174-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9060929-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9066854-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2009094742-A1 |
| priorityDate |
1998-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |