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filingDate 2000-12-07^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-04-23^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_abe6de604ca3445fe0dd6d4d80cba4ff
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fd6c38ba0641abdfb87fd151e0f4e33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_efddc8a7e533280aa445d2888e8e76fb
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baf5e0edcaa3c2116efdeebb28cd7590
publicationDate 2002-04-23^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6376489-B1
titleOfInvention Cyclic AMP-specific phosphodiesterase inhibitors
abstract Novel compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory disease and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
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