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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-06
filingDate 2000-12-01^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-11-19^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a83ab3b6d0ac56b6601c6f38e034be85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10dbda03e9e625339c1004b288df84be
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publicationDate 2002-11-19^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6482805-B2
titleOfInvention AZT derivatives exhibiting spermicidal and anti-viral activity
abstract Contraceptive activity as well as anti-viral protection can be provided by contraceptive compositions containing a pyrimidine-based nucleoside or nucleotide exhibiting spermicidal or sperm-immobilizing activity. In one example, the active ingredient contains a thymine ring (e.g. AZT) that has 5-halo, 6-alkoxy substitution. Additional improvements in anti-HIV activity for certain AZT derivatives are seen by providing the pentose ring of AZT with aryl phosphate substitution.
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