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filingDate 1999-01-07^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-12-03^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c36ea329aaacd1358a49daef56dadef6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7690d4a9501a424cd057ff8c0ae0761
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publicationDate 2002-12-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6489470-B1
titleOfInvention Process for the preparation of cefpodoxime proxetil diastereoisomers
abstract A process for increasing the diastereoisomeric ratio (B/A+B), wherein B is the more apolar and A is the more polar of two diastereoisomers, of a mixture of diastereoisomers of a compound of formulathe diastereoisomers being with respect to the carbon atom marked with a star in formula I, comprising treating a mixture of diastereoisomers of a compound of formula I with alcohol and water and isolating the precipitated compound of formula I in an increased diastereoisomeric ratio (B/A+B) of 0.5 to 0.6.
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