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filingDate 1995-11-30^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2002-12-24^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9d3f067c50d5cf67571ca7591efdd94
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publicationDate 2002-12-24^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6497881-B1
titleOfInvention High efficiency tissue specific compound delivery system using streptavidin-protein a fusion protein
abstract The present invention relates to methods and compositions that can be employed to introduce toxins and nucleic acids into the cytoplasm or nucleus of a eukaryotic cell, particularly a cell of a higher vertebate. The invention particularly concerns the use of a fusion protein of streptavidin and protein A sequences to form a non-covalent complex of a toxin or nucleic acid and an antibody.
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