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filingDate 2000-11-17^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2003-01-28^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6511677-B1
titleOfInvention Polymerizable fatty acids, phospholipids and polymerized liposomes therefrom
abstract The invention relates to an oral drug delivery system which delivers biologically active substances to the mucosal tissue of the intestine utilizing novel polymerized liposomes. Novel polymerizable fatty acids having a polymerizable group, a surfactant group, and a functional group, and optionally coupled to ligands which target mucosal tissue in the intestine are disclosed. Novel negatively charged polymerizable lipids which have phosphatidyl inositol (PI), phosphatidyl glycerol (PG) or phosphatidyl serine (PS) groups on a polymerizable backbone are also described.
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0JB31
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0JB28
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http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID483
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226437184
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0JB16
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865Y1
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0JB22
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP37997
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID461472
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID415824671
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0JB23
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID128961115
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID514876
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC0JB21
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