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filingDate 2002-04-25^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2003-06-24^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6583140-B2
titleOfInvention 2-substituted thiazolidinones as beta-3 adrenergic receptor agonists
abstract This invention provides compounds of Formula I having the structurewherein:A, X, Y, Z, R1, R2, R3, R4, R5, and R6 are as defined hereinbefore or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.
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