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filingDate 2000-09-25^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62302a4e05b38f8a4c9515cb494e6100
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publicationDate 2003-08-05^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6602672-B1
titleOfInvention Recombinant construct encoding epitope tagged PrP protein
abstract DNA constructs are provided of epitope-tagged proteins or protein fragments which are conveniently purified with immunoaffinity chromatography such as epitope-tagged prion proteins (PrP). Transgenic animals expressing an epitope-tagged protein are provided, including transgenic animals expressing epitope-tagged PrP. Methods for distinguishing between the conformational shapes of a protein and a convenient method for isolating a tagged protein by immunoaffinity chromatographic methods are provided.
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