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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-55
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
filingDate 2000-03-31^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-08-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_400b6fef9e08bbb382f45248528f8f89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a83ab3b6d0ac56b6601c6f38e034be85
publicationDate 2003-08-12^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6605589-B1
titleOfInvention Cathepsin inhibitors in cancer treatment
abstract Embodiments of the present invention provide methods for inhibiting tumor cell growth, or treating cancer cells, in a subject through the administration of a cathepsin inhibitor or inhibitors. Methods for inhibiting inflammatory disease cells as well as other cathepsin expressing cells in a subject with a cathepsin inhibitor or inhibitors are also within the present invention. Furthermore, the present invention relates to inducing cytotoxicity or apoptosis in cells by administering a cytotoxic or an apoptotic dose of a cathepsin inhibitor or inhibitors to the cell. Finally, the present invention relates to the administering of cathepsin expressing vectors to tumor cells so as to inhibit the tumor cells growth.
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