Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcb146c68b67089013b4c7a614504254 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1282 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-065 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-33 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 |
filingDate |
1998-05-26^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2003-09-02^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6010d9f1a18c87aaf72ec1afcbecac45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e9a80c9b75d5d1ef5c1fab30e07ac83 |
publicationDate |
2003-09-02^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-6613329-B1 |
titleOfInvention |
Vaccine and antitoxin for treatment and prevention of C. difficile disease |
abstract |
The present provides neutralizing antitoxin directed against C. difficile toxins. These antitoxins are produced in avian species using soluble recombinant C. difficile toxin proteins. The avian antitoxins are designed so as to be orally administrable in therapeutic amounts and may be in any form (i.e., as a solid or in aqueous solution). Solid forms of the antitoxin may comprise an enteric coating. These antitoxins are useful in the treatment of humans and other animals intoxicated with at least one bacterial toxin. The invention further provides vaccines capable of protecting a vaccinated recipient from the morbidity and mortality associated with C. difficile infection. These vaccines are useful for administration to humans and other animals at risk of exposure to C. difficile toxins. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007146139-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005266050-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007104737-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7179611-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007146139-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011014178-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2986316-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014253685-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7227010-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7037680-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003018170-A1 |
priorityDate |
1989-10-31^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |