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filingDate 1998-05-26^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2003-09-02^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6010d9f1a18c87aaf72ec1afcbecac45
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e9a80c9b75d5d1ef5c1fab30e07ac83
publicationDate 2003-09-02^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6613329-B1
titleOfInvention Vaccine and antitoxin for treatment and prevention of C. difficile disease
abstract The present provides neutralizing antitoxin directed against C. difficile toxins. These antitoxins are produced in avian species using soluble recombinant C. difficile toxin proteins. The avian antitoxins are designed so as to be orally administrable in therapeutic amounts and may be in any form (i.e., as a solid or in aqueous solution). Solid forms of the antitoxin may comprise an enteric coating. These antitoxins are useful in the treatment of humans and other animals intoxicated with at least one bacterial toxin. The invention further provides vaccines capable of protecting a vaccinated recipient from the morbidity and mortality associated with C. difficile infection. These vaccines are useful for administration to humans and other animals at risk of exposure to C. difficile toxins.
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005266050-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007104737-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7179611-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007146139-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011014178-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2986316-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2014253685-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7227010-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7037680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003018170-A1
priorityDate 1989-10-31^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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