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filingDate 2001-06-22^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec00b174b14e1b15165852c53ade1041
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publicationDate 2003-11-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6649347-B2
titleOfInvention Use of methylated nucleic acid segments for isolating centromere DNA
abstract The invention provides efficient methods for the isolation of centromeres from potentially any organism. The methods may comprise the steps of: a) preparing a first sample of genomic DNA from a selected species; b) obtaining a plurality of methylated nucleic acid segments from the genomic DNA; and c) screening the methylated nucleic acid segments to identify a centromere nucleic acid sequence.
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