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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93c03006967d19791ce39a531a473943
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publicationDate 2003-11-25^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6652849-B2
titleOfInvention Anaerobe targeted enzyme mediated prodrug therapy
abstract A genetically-engineered anaerobic organism is provided which, under anaerobic conditions present in a solid tumor, produces an enzyme capable of catalyzing the conversion of a prodrug to its highly cytotoxic product in situ and methods of treating tumors using same.
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