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filingDate 2001-02-22^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2004-01-13^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c40a8f70bfcf0e3b653f285a4f3261d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c5c382a02d29ea266199bae8743cd9b
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publicationDate 2004-01-13^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6677343-B2
titleOfInvention Substituted piperazine compounds
abstract Novel compounds of the general formula:and pharmaceutically acceptable acid addition salts thereof, wherein the compounds are useful in therapy to protect skeletal muscles against damage resulting from trauma or to protect skeletal muscles subsequent to muscle or systemic diseases such as intermittent claudication, to treat shock conditions, to preserve donor tissue and organs used in transplants, in the treatment of cardiovascular diseases including atrial and ventricular arrhythmias, Prinzmetal's (variant) angina, stable angina, and exercise induced angina, congestive heart disease, and myocardial infarction.
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