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filingDate 2003-02-27^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b7bea5e85cf26a70852f675e852d4b
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publicationDate 2004-11-02^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6812227-B2
titleOfInvention Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
abstract Compounds of the formula: n are useful in treating disease conditions mediated by TNF-α, such as rheumatoid arthritis, osteoarthritis, sepsis, AIDS, ulcerative colitis, multiple sclerosis, Crohn's disease and degenerative cartilage loss.
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