| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-03
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0611
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2001-11-01^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-12-07^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbd1fb6264c99589d6f42961aa240828
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76de332b00eda9c6b101e14f973db927
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b08572bf6782f5fe1a5c893bdecf1fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5f0bedab83791268f26e63decc6e665 |
| publicationDate |
2004-12-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6828473-B2 |
| titleOfInvention |
Modulation of PDE11A activity |
| abstract |
The invention provides genetically-modified non-human mammals and genetically-modified animal cells containing a functionally disrupted PDE11A gene. Also provided by the invention are methods of screening for agents that modulate PDE11A to modulate spermatogenesis, methods of treating mammals to modulate spermatogenesis, and methods of modulating cAMP and cGMP signal transduction in cells that express PDE11A. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8318137-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010087509-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007184026-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7615626-B2 |
| priorityDate |
2000-11-01^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |