| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_23a4e0c875bf1ac2b8a3b76517de6c7d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 |
| filingDate |
2000-03-28^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2005-04-12^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fc3bd7f1bf3bdc9dd950e6b8e812935
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66c6c0a54e05fcb6b6b8a89fd3f747ac |
| publicationDate |
2005-04-12^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-6878514-B1 |
| titleOfInvention |
Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof |
| abstract |
The invention described herein encompasses methods of preventing or treating disorders caused by oxidative damage by an aging-specific isoform of NADH oxidase (AR-NOX). The invention encompasses methods of assaying, screening, and identifying agents that inhibit AR-NOX, as well as methods using ubiquinone to inhibit the ability of AR-NOX to generate reactive oxygen species. These agents may be formulated into pharmaceutical compositions in the prevention and treatment of disorders caused by oxidative damage. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7829080-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008175935-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005142628-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011217401-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8465939-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007104810-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2005226947-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7205127-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007258966-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006053148-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009246152-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009246153-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006134794-A1 |
| priorityDate |
1999-03-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |