http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7054685-B2

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filingDate 2002-08-08^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2006-05-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7054685-B2
titleOfInvention Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
abstract A method for delivery of an agent to a cell using electroporation is disclosed. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5746
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID4133
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID74297
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID127850182
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID16666
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395875
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395874
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5364430
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396577
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID36314
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396576
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID31703
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226394280
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID127448226
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID5363269
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395471
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID128857037
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226433303
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226396057

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