| abstract |
An agent which comprises, as an active ingredient, a radiolabeled compound as represented by the following formula or a pharmaceutically acceptable salt thereof: n nwherein R 1 denotes hydrogen, or a linear- or branched-chain alkyl group having 1–8 carbon atoms, R 2 denotes hydrogen, hydroxyl or a halogen substituent, R 3 denotes hydrogen or fluorine substituent, R 4 denotes oxygen, sulfur, or a methylene substituent, and R 5 denotes a radioactive halogen substituent.n n The agent is stable in vivo, and either stays in cells or is incorporated in DNA, thus serving for diagnosis of tissue proliferation activity or treatment of proliferative disease. |