http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7132536-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1542e8802a0e6a7a8a7c6bd5627eb857 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 |
| filingDate | 2004-04-21^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-11-07^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b06325d0e3df665f369016972d80e4d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b25a1235977e0d2a67f8c4f5d5f5f7ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad7d688d099d5b63004a5caf5737c5df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a591d513d0cfb8ff06a8233e273bb354 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c64862c7c0e07bebee3ce978ed692514 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8289da2bee295032d8bd91b86a5d11d |
| publicationDate | 2006-11-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7132536-B2 |
| titleOfInvention | Triaza- and tetraaza-anthracenedione derivatives, their preparation and their use as pharmaceuticals |
| abstract | The present invention relates to triaza- and tetraaza-anthracenedione derivatives of the formula I, n nwherein A, B and R 1 to R 5 are as defined herein. The compounds of formula I are valuable pharmacologically active compounds. They are useful in the treatment of various disease states including cardiovascular disorders such as atherosclerosis, thrombosis, coronary artery disease, hypertension and cardiac insufficiency. They upregulate the expression of the enzyme endothelial nitric oxide (NO) synthase and can be applied in conditions in which an increased expression of said enzyme or an increased NO level or the normalization of a decreased NO level is desired. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical preparations comprising them. |
| priorityDate | 2003-04-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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