http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7297790-B2

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14
filingDate 2003-12-24^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-11-20^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90d18c6cb8d2cea248087123223ffbfa
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publicationDate 2007-11-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7297790-B2
titleOfInvention Anhydrous mirtazapine crystals and process for preparing the same
abstract Low-hygroscopic anhydrous mirtazapine crystals having a hygroscopic degree of not more than 0.6% by weight when the crystals are stored in the air having a relative humidity of 75% at 25° C. under atmospheric pressure for 500 hours; a process for preparing anhydrous mirtazapine crystals having a hygroscopic degree of not more than 0.6% by weight when the crystals are stored in the air having a relative humidity of 75% at 25° C. under atmospheric pressure for 500 hours, comprising drying crystals of mirtazapine hydrate; a crystal of a mirtazapine hydrate represented by the formula (I): n nwherein n is an integer of 1 to 5; and a process for preparing crystals of a mirtazapine hydrate, comprising crystallizing a crude mirtazapine using a water-soluble organic solvent and water. The anhydrous mirtazapine crystals can be suitably used, for instance, as an antidepressant.
priorityDate 1999-11-24^^<http://www.w3.org/2001/XMLSchema#date>
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