http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7326416-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef416fe4f66ebb1021cecfb0ba5ae45d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-16 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4703 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2003-07-21^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2008-02-05^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de801b7b329dff883642c9de04777f83 |
| publicationDate | 2008-02-05^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-7326416-B2 |
| titleOfInvention | Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1(INI1)/hSNF5 |
| abstract | Peptides comprising an Rpt1 domain of an INI1/hSNF5 which inhibit HIV-1 production in a human cell, and vectors encoding those peptides are provided. Also provided are methods of inhibiting HIV-1 production in a cell, or spread of the HIV-1 to another cell, by treating the cells with the above peptides or vectors. Other methods of inhibiting HIV-1 production in a cell, or spread of the HIV-1 to another cell, by inhibiting production of INI1/hSNF5 are provided. Additionally, methods of determining whether a test compound inhibits HIV-1 virion production in a mammalian cell, or spread of the HIV-1 to another cell, are provided. Those methods comprise determining whether the test compound inhibits the production of INI1/hSNF5 or disrupts the interaction of HIV-1 integrase with INI1/hSNF5. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007259358-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8008470-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009247610-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006275748-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7514233-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846677-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2008206742-A1 |
| priorityDate | 2002-07-19^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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